Below is an arbitrary selection. You can find much more options on your regular tool (expedia, hotels.com, airbnb) or via http://www.tourisme-rennes.com/en/hotels-accommodation.
In the list we give the walking time to Metro Saint Anne, but there are usually closer metro stations (it just gives an indication of walking distance to the main station).
- Hôtel des Lices (***)
Web site: http://www.hotel-des-lices.com/c/247/p/2ff5df55a87776c54617f0697c30ac31/hotel-des-lices-rennes-centre-ville-ille-et-vilaine-bretagne.html
Address: 7 place des Lices, 35000 Rennes
Tel. : +33 2 99 79 14 81
Location: Metro station Saint Anne (about 2 minutes walking), Train station (about 23 minutes walking) - Mercure Rennes Centre Parlement (****)
Web site : http://www.accorhotels.com/fr/hotel-1056-hotel-mercure-rennes-centre-parlement/index.shtml
Address: 1 rue Paul Louis Courier, 35000 Rennes
Tel. : +33 2 99 78 82 20
Location: Metro station République (about 3 minutes walking), Train station (about 12 minutes walking) - Hôtel Anne de Bretagne (***)
Web site: http://www.hotel-rennes.com/
Address: 12 rue Tronjolly, 35000 Rennes
Tel. : +33 2 99 31 49 49
Location: Metro station République (about 5 minutes walking), Train station (about 11 minutes walking)- Hôtel Lanjuinais (**)
Web site: http://hotel-lanjuinais.com/
Address: 11 rue Lanjuinais, 35000 Rennes
Location: Metro station République (about 5 minutes walking), Train station (about 13 minutes walking) - Le Nemours (**)
Web site: http://www.hotelnemours.com/
Address: 5 rue de Nemours, 35000 Rennes
Location: Metro station République (about 3 minutes walking), Train station (about 12 minutes walking) - Le Garden (**)
Web site: http://www.hotel-garden.fr/fr
Address: 3 rue Duhamel, 35000 RENNES
Location: Metro station République (about 8 minutes walking), Train station (about 7 minutes walking) - Hôtel Angelina (**)
Web site: http://www.angelina-hotel.com/
Address: 1 quai Lamennais, 35000 Rennes
Location: Metro station République (about 1 minutes walking), Train station (about 15 minutes walking)
- Hôtel Mercure Rennes Centre Gare (****)
Web site: http://www.accorhotels.com/fr/hotel-1249-hotel-mercure-rennes-centre-gare/index.shtml
Address: 1 rue du Capitaine Maignan, 35000 Rennes
Location: Metro station République (about 11 minutes walking), Train station (about 6 minutes walking) - Le Victoria (***)
Web site: http://www.hotel-levictoria.com/
Address: 35 avenue Janvier, 35000 Rennes
Location: Metro station République (about 11 minutes walking), Train station (about 4 minutes walking) - Hôtel le Sévigné (***)
Web site: http://www.hotellesevigne.fr/
Address: 47 bis avenue Janvier, 35000 Rennes
Location: Metro station République (about 12 minutes walking), Train station (about 3 minutes walking) - Hôtel Kyriad Rennes Centre (***)
Web site: http://www.kyriad-rennes-centre.fr/fr
Address: 6 place de la gare, 35000 Rennes
Location: Metro station République (about 13 minutes walking), Train station (about 1 minutes walking) - Arvor Hôtel (**)
Web site: http://www.arvorhotel.com/
Address: 31 rue Barthou, 35000 Rennes
Location: Metro station République (about 14 minutes walking), Train station (about 2 minutes walking) - Hôtel CITOTEL Le Bretagne
Web site: http://www.hotel-le-bretagne.fr/
Address: 7 bis place de la gare, 35000 Rennes
Location: Metro station République (about 13 minutes walking), Train station (about 1 minutes walking) - Hôtel IBIS Rennes Centre Gare Sud
Web site: http://ibishotel.ibis.com/
Address: 15 rue de Châtillon, Esplanade Fulgence Bienvenue, 35000 Rennes
Location: Metro station République (about 17 minutes walking), Train station (about 2 minutes walking) - RésidHome Apparthotel
Web site: http://www.sejours-affaires.com/residence-hoteliere-aparthotel-rennes-29.html
Address: 23 rue de Chatillon, 35000 RENNES
Location: Metro station République (about 17 minutes walking), Train station (about 2 minutes walking)
- Hôtel Lanjuinais (**)